Program

Agenda

Friday, December 10: Day 1

 7:30 AM - 8:00 AMRegistration and Continental Breakfast
   
 8:00 AM - 8:15 AMWelcome and Opening
   
 Session 1Non-Asthmatic Airway Diesease: Clinical Update
Moderator to be announced
   
 8:15 AM - 8:45 AMRole of Sinitus/Rhinitus in Asthma: The One Airway Hypothesis
Robert P. Schleimer, PhD
   
 8:45 AM - 9:15 AMVCD: The Great Masquerader
Speaker to be announced
   
 9:15 AM - 9:45 AMGERD: Cause, Effect, or Cofounder?
Speaker to be announced
   
 9:45 AM - 10:00 AMBreak
   
 10:00 AM - 10:30 AMCOPD Phenotypes
Speaker to be announced
   
 10:30 AM - 11:00 AMValves and Other New Approaches
Speaker to be announced
   
 11:00 AM - 11:30 AMWhen ILD Is Associated with Airway Disease
Speaker to be announced
   
 11:30 AM - 12:30 PMMeet-the-Professors Lunch
   
 Session 2 Topic - Asthma Phenotypes: Implications for Disease Mechanisms and Therapy
Moderator to be announced
   
 12:30 PM - 1:00 PMAdult Asthma: One Disease or Many?
Eugene R. Bleecker, MD
   
 1:00 PM - 1:30 PMAsthma and Obesity: Different Pheotype, Different Cause, or Both?
Fernando Holguin, MD, MPH
   
 1:30 PM - 2:00 PMPsychologic Stress, Viruses, and Asthma Exacerbations
Sheldon Cohen, PhD
   
 2:00 PM - 2:30 PMBiologics in Asthma Therapy: How They Help Us with Phenotyping
William Busse, MD
   
 2:30 PM - 2:45 PMPanel Discussion
   
 2:45 PM - 3:00 PMBreak
   
 Session 3Linking the Phenome to the Genome to Identify Endotypes
Moderator: Deborah Meyers
   
 3:00 PM - 3:30 PMRacial/Ethnic Differences and the Impact on Asthma Phenotypes
Kathleen C. Barnes, MD
   
 3:30 PM - 4:00 PMEpigenetics: The Environment's Footprint on the Phenome
David A. Schwartz, MD
   
 4:00 PM - 4:30 PMUsing Genomic Expression to Identify Asthma Phenotypes
Prescott G. Woodruff, MD, MPH
   
 4:30 PM - 5:00 PMUnderstanding the Mechanisms by which Genetic Differences Influence Immune Response
Donata Vercelli, MD
   
 5:00 PM - 5:15 PMPanel Discussion
   
 5:15 PM - 5:20 PMClosing Remarks
   
 Post-Scientific Session Events
   
 5:30 PM - 7:00 PMPoster Reception, with facilitator Lauren Cohn, MD
   
 Banquet Dinner
   
 7:00 PM - 9:00 PMKeynote Presentation
Jeffrey M. Drazen, MD
   


Saturday, December 11: Day 2 - Host, Pathogen, and Immune Responses of Relevance to Asthma

 7:30 AM - 8:00 AMRegistration and Continental Breakfast
   
 8:00 AM - 8:15 AMWelcome and Opening Remarks
   
 Session 4The Intersection of Pathogens and Asthma: From Allergic Sensitization to Phenotyping
Moderator: Tina V. Hartert, MD, MPH
   
 8:15 AM - 8:45 AMHygiene Hypothesis and Allergic Sensitization: The European and American Paradox
Erika von Mutius, MD, MSc
   
 8:45 AM - 9:15 AMEvaluating the Microbiome in Asthma: What Organisms Are to Blame and Thank?
Speaker to be announced
   
 9:15 AM - 9:45 AMViral Infections in Relation to Asthma Development and Severity: Cause or Susceptability?
Robert F. Lemanske, Jr., MD
   
 9:45 AM - 10:15 AMViral Impact on Immune Responses and Asthma
R. Stokes Peebles, MD
   
 10:15 AM - 10:30 AMPanel Discussion
   
 10:30 AM - 10:45 AMBreak
   
 Session 5 First Lines of Host Defense: The Conversion of Innate with Adaptive Responses
Moderator: Robert P. Schleimer, PhD
   
 10:45 AM - 11:15 AMThe Asthmatic Airway Mucosa: Has the Host's Defense Gone Awry?
Patrick Holt, DSc
   
 11:15 AM - 11:45 AMMast Cells
Stephen J. Galli, MD
   
 11:45 AM - 12:15 PMChitinases: Intiating Th2
Jack A. Elias, MD
   
 12:15 PM - 12:45 PMMast Cells and Augmentation of Th2
Sally Wenzel, MD
   
 12:45 PM - 1:00 PMPanel Discussion
   
 1:00 PM - 2:00 PMLunch
Kevin da Silva, PhD
   
 Session 6Th17: Too Much, Too Little (Or Too Late)?
Moderator: Sarah Gaffen, PhD
   
 2:00 PM - 2:30 PMC-Kit Signaling in DCs and Induction of Th17
Prabir Ray, PhD
   
 2:30 PM - 3:00 PMTh17, Neutrophilia, and Steroid Resistant
Jay K. Kolls, MD
   
 3:00 PM - 3:30 PMTh17/Th1 Plasticity and Mucosal Immunity
Speaker to be announced
   
 3:30 PM - 3:45 PMPanel Discussion
   
 3:45 PM - 4:00 PMBreak
   
 Session 7T Regulatory Cells in Many Flavors and Their Role in Allergic Inflammation
Patrick Holt
   
 4:00 PM - 4:30 PMTopic to be announced
Anuradha Ray, PhD
   
 4:30 PM - 5:00 PMTregs Targeting Tissue DCs to Dampen T Effector Function
Marsha Wills-Karp, PhD
   
 5:00 PM - 5:30 PMPeptide Immunotherapy and Tregs: Glimmers of Hope
Mark Larche, PhD
   
 5:30 PM - 5:45 PMPanel Discussion
   
 5:45 PM - 6:00 PMClosing - Leading Thinkers from Industry
Speakers to be announced