Rubin Tuder, MD
The Johns Hopkins University School of Medicine and Bloomberg School of Public Health
Baltimore, Maryland

Presentation Title
Pathobiology of Pulmonary Hypertension (Summary of Presentation)

Dr. Tuder is presently Professor of Pathology at the Johns Hopkins University School of Medicine.  He heads the Division of Cardiopulmonary Pathology, with secondary appointments in the Division of Pulmonary and Critical Care Medicine, Department of Medicine, School of Medicine, and the Division of Physiology, School of Public Health.   Prior to joining the Hopkins faculty in 2001, Dr. Tuder served as an assistant and associate professor of pathology at the University of Colorado Health Sciences Center. 

A graduate of the University of Sao Paulo School of Medicine, Dr. Tuder completed his residency there in anatomic pathology.  He pursued a postdoctoral fellowship in the Department of Pathology of the Stanford University, where he developed his interest in the study of endothelial cells.  He then returned to Sao Paulo, where he worked for three years in the Laboratory of Transplant Immunology.

Dr. Tuder’s current major area of interest is the pathobiology of pulmonary hypertension and emphysema.  His work in pulmonary hypertension, which developed from his interest in the pulmonary circulation, has been carried out in close collaboration with and under the mentorship of Dr. Norbert Voelkel.  Drs. Voelkel and Tuder developed the concepts of the "neoplastic paradigm of pulmonary hypertension" and of the occurrence of the disease through the selection of an apoptosis-resistant endothelial cell.  Over the past seven years, Dr. Tuder has expanded his interests to include the role of lung endothelial cells, apoptosis, and alveolar cell maintenance in the pathogenesis of emphysema.