Jay L. Zweier, MD, PhD
Davis Heart and Lung Research Institute
Ohio State University
Columbus, Ohio
Organizing Committee
Session Chair
Mechanisms of Nitrite Bioactivation
Presentation Title
Nitrite as a Source of Nitric Oxide in the Normal and Ischemic Heart
Dr Zweier received his baccalaureate degrees in physics and mathematics at Brandeis University in 1976. After PhD training in biophysics at the Albert Einstein College of Medicine, he pursued medical training at the University of Maryland School of Medicine and received his MD in 1980. Subsequently he completed his residency in internal medicine followed by his cardiology fellowship at Johns Hopkins in 1986. In 1987, he joined the faculty of The Johns Hopkins University School of Medicine. At Hopkins, he established the molecular and cellular biophysics laboratories and the institutional Electron Paramagnetic Resonance Center. He served as Co-Director of The Johns Hopkins Specialized Center of Research (SCOR) in Ischemic Heart Disease and the Ischemic Heart Disease Heart Research Program. In 1998 he was promoted to the rank of Professor and in 2000, he was appointed as Chief of Cardiology Research, directing the cardiovascular research program at the Johns Hopkins Bayview Campus. In addition to serving as Professor of Medicine in the Cardiology and Pulmonary Divisions, Dr Zweier also held appointments as Professor of Radiology and Environmental Health Sciences in the Schools of Medicine and Public Health, respectively. He was elected as a fellow in the American College of Cardiology in 1995 and the American Society of Clinical Investigation in 1994. In July of 2002, Dr Zweier joined The Ohio State University College of Medicine as the Director of the Davis Heart & Lung Research Institute and as the John H. and Mildred C. Lumley Chair in Medicine.
Dr Zweier has had numerous national and international advisory appointments. He is a member of the National Institutes of Health Reviewers Reserve, and he served as special reviewer for the BBCB Study Section, the National Center for Research Resources for Magnetic Resonance Center Programs, the National Heart, Lung and Blood Institute and the National Cancer Institute for Program Project Grants. He has also served on the Council for the National Cancer Institute. He has reviewed for the Veterans’ Administration Cardiovascular Study Section, the National Science Foundation and American Heart Association grant programs. Internationally, he has served as reviewer for the Welcome Trust, the Medical Research Council of Canada and the Medical Research Council of the United Kingdom. He has been a member of numerous international advisory boards for magnetic resonance centers including those at Dartmouth University, University of Chicago, Oklahoma Medical Research Foundation, Albert Einstein College of Medicine and the National Center for In vivo ESR Spectroscopy Imaging, in Japan at the Yamagata Technopolis Foundation. He serves on the editorial boards of numerous journals including the Journal of Clinical Investigation, Circulation, Circulation Research, British Journal of Pharmacology, Antioxidants and Redox Signaling, Current Topics in Biophysics, Methods in Enzymology and the American Journal of Physiology. He also actively reviews for other journals including Science, Nature, Proceedings of the National Academy of Sciences, the Journal of Biological Chemistry, Journal of Magnetic Resonance and Magnetic Resonance in Medicine. He has been the recipient of more than 75 endowed lectureships and awards in the US and abroad. These awards include the Virchow Prize for medical research, the WW Smith award for innovative cardiology research, the Upjohn Award for outstanding investigation from the International Society for Heart Research, the Louis N. Katz Basic Research Award from the American Heart Association, the Clinician Scientist and Established Investigator awards from the American Heart Association, the DuPont-Merck award for research excellence, the Alice Hamilton Award for Biological Sciences.
Dr Zweier has published over 200 peer reviewed published manuscripts in the fields of cardiovascular research, free radical biology and magnetic resonance. As principal investigator, program leader, project leader and investigator, Dr Zweier has been awarded over $60 million dollars in support from the National Institutes of Health and other funding agencies.