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Department of Health and Human Services          National Institutes of Health

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Organizing Committee

Rakesh Patel, PhD

Rakesh P. Patel, PhD
Department of Pathology
University of Alabama, School of Medicine
Birmingham, Alabama

Organizing Committee

Presentation Title
Elucidating the Relative Roles of Nitrite, ATP and SNO-Hb in mediating Red-cell Dependent Hypoxic Vasodilation using the b93cys Knockout Mouse

Dr Patel received his PhD from the University of Essex, United Kingdom, in 1996. He joined the UAB Department of Pathology as a postdoctoral Fellow and is now an Associate Professor. Dr Patel is involved in research projects centered on defining the molecular mechanisms by which reactive oxygen and nitrogen species modulate acute and chronic inflammation. These involve understanding i) what factors regulate endothelial cell function during inflammation and ii) the reactions that occur between red blood cells, nitric oxide and nitrite during hypoxia and specifically how these regulate nitric oxide function in the vascular compartment iii) assessing the clinical efficacy of nitrite and inhaled nitric oxide in preventing ischemia-reperfusion injury.