Andre Dejam, MD, PhD
Department of Internal Medicine
Brigham and Women's Hospital
Boston, Massachusetts

Presentation Title
Mechanism of NO Formation, Tolerance and Endocrine Bioactivity of Nitrite (Summary of Presentation)

Dr Dejam is presently completing a Residency in the Hemidoc-Program of the Department of Medicine at Brigham and Women’s Hospital.  Prior to this, from 2001-2003, he was a Research Fellow at the University of Duesseldorf, Division of Cardiology, Angiology Pneumology, and Intensive Care Medicine at Heinrich-Heine-University Duesseldorf.  From 2003-2005, Dr Dejam was a Clinical Research Fellow at the National Institutes of Health, Molecular Medicine Branch, NIDDK.

Dr Dejam received his MD and PhD from the University of Hannover.  His research interests include: endothelium-dependent regulation of vascular tone; participation of the erythrocyte in the modulation of NO bioavailablity in humans;  mechanisms of beta-cell death in the pathogenesis of diabetes mellitus; and regulation of oxygen delivery to the tissues.

Dr Dejam has written 25 original contributions in peer-reviewed journals with two others in revision or preparation, three book chapters, and 17 abstracts.  In 2004, Dr Dejam received the Young Investigator Award at the Annual Meeting of the Society of Free Radical and Biology in the US Virgin Islands; and in 2005, he won the NIH Science award in recognition of outstanding research in the field of nitrite:  Role of Nitrite in Physiology, Pathophysiology, and Therapeutics.  He has worked on three NIH Human Studies’ Protocols:  Evaluation of the Mechanism of NO Formation and the Pharmacokinetics of Systemic Nitrite Infusion; Evaluation of Systemic Nitrite Infusion and its Effect on Exercise Physiology and Metabolism; and Studies of the Natural History of Sickle Cell Disease and Other Hemolytic Disorders.