Department of Medicine
Harvard Medical School
Boston, Massachusetts
Cardiac Metabolism and Mitochondrial Function in Heart Failure (Oct. 7, 1:40 PM)
Presentation Summary
Dr. Tian is an Associate Professor of Medicine at Harvard Medical School and a Physiologist at Brigham and Women’s Hospital. She has held both positions since 2005. Prior to that, Dr. Tian was an Assistant Professor of Medicine (1999-2005) and an Instructor in Medicine (1997-1999) at Harvard Medical School.
Dr. Tian obtained her MD from West China University of Medical Sciences in China in 1986 and his PhD from the University of Aarhus in Denmark in 1992.
Her current research is focused on understanding the functional significance of altered substrate metabolism in the heart using transgenic mice in combination with multi-nuclei nuclear magnetic resonance techniques. This line of research seeks to generate a basis for a metabolic therapy for heart failure and cardiac lipotoxicity in obesity and diabetes. Another line of research focuses on metabolic signaling in the heart. Her group was the first to report an increased activity of AMPK-activated protein kinase (AMPK), an energy sensor and master switch of metabolism, in hypertrophied hearts.
