Welcome: Opening Remarks

8:50 AM—9:00 AM

J. Perren Cobb, MD, and Jeremy M. Berg, PhD

Epigenetics and Stress
Chair: Robert L. Danner, MD

Epigenetic Regulation is a Key Driver of the Macrophage and Dendritic Cell Phenotype During Severe Sepsis
Steven L. Kunkel, PhD

Epigenetics of Gene Reprogramming in Severe Systemic Inflammation
Charles (Cash) E. McCall, MD

Epigenetic Control in the Immune System
Tian Chi, MD, PhD

10:15 AM—10:45 AM

Panel Discussion

10:45 AM—11:00 AM

Break/Poster Viewing

Oral Posters: Poster Presentation
Chair: Anthony F. Suffredini, MD

#7   Role of Chromatin-Associated Proteins HMGB1 and H1 in Epigenetic Silencing During Severe Systemic Inflammation
Mohamed A. Elgazzar, PhD

#8  Altered Global Gene Expression in First Trimester Placentas of Women Destined to Develop Preeclampsia
Sandra A. Founds, PhD

#9  A Potential Association of Epigenetic Mechanisms with Immunomodulation of Peripheral Blood Mononuclear Cells by Extracorporeal Ultraviolet Treatment
Dmitry Grigoryev, MD, PhD

#12  The Role of the Genome in the Metabolic Response to Injury: A Preliminary Report of 1300 Trauma Patients, Multiple Physiologic Pathways, and 61 Single Nucleotide Polymorphisms
Jeffrey A. Canter

Lunch/Poster Viewing

New Technology and Applications
Chair: Anthony F. Suffredini, MD

1:00 PM—1:25 PM

Microfluidic Tools for Clinical Sample Processing
Kenneth T. Kotz, PhD

Riboleukogram: an EKG for Immunity
J. Perren Cobb, MD

1:50 PM—2:15 PM

In Pursuit of GWAS Findings: Genotyping, Sequencing, and Beyond
Meredith Yeager, PhD

2:15 PM—2:45 PM

Panel Discussion

2:45 PM—3:00 PM

Break

Phenomics: The Role of Information Systems
Chair: J. Perren Cobb, MD

3:00 PM—3:25 PM

Bioinformatics and Computational Biology at NIGMS/NIH: Building Bridges to Discovery
Karin A. Remington, PhD

3:25 PM—3:50 PM

Integrating Data, Models, and Reasoning in Critical Care
Roger G. Mark, MD, PhD

3:50 PM—4:15 PM

The Reactome Knowledgebase of Biological Reactions and Pathways, a Window into Functional Genomics
Lincoln D. Stein, MD, PhD

4:15 PM—4:45 PM

Panel Discussion

Closing Remarks and Peer Awards

J. Perren Cobb, MD

5:00 PM—6:00 PM

Poster Session Reception / Peer Review

5:45 PM—6:15 PM

Critical Illness and Injury – Scientific Interest Group
Annual Meeting
Natcher Conference Center
Balcony Room C
NIH Staff Only