November 15, 2007

9:00 - 9:05 AM

Welcome
Anthony Suffredini, MD

Forging a Critical Alliance
What are the Research Needs of the United States Critical Illness and Injury Community?
Leaders: Scott Somers, PhD and J. Perren Cobb, MD
9:05 - 9:20 AM	Development of a National Network for a Critical Care Improvement: the Partnership for Excellence in Critical Care Henry J. Mann, Pharm.D.
9:20 - 9:35 AM	A Translational Research Paradigm for Critical Care Derek C. Angus, MD, MPH
9:35 - 9:50 AM	Canadian Critical Care Trials Network John C. Marshall, MD
9:50 - 10:05 AM	Break

Leaders: Andrea Harabin, PhD and J. Perren Cobb, MD
10:05 - 10:15 AM	A Perspective of the Research Needs of the Critical Care Community Frederick P. Ognibene, MD
10:15 - 10:25 AM	Barriers to Increasing Research in Critical Care David H. Ingbar, MD
10:25 - 10:35 AM	American College of Chest Physicians Alvin V. Thomas, Jr., MD
10:35 - 10:45 AM	American Association for the Surgery of Trauma David B. Hoyt, MD
10:45 - 11:30 AM	Panel Discussion
11:30 - 12:30 PM	Lunch

**Phenomics**
Leader: Ramona Hicks, PhD
12:30 - 1:00 PM	Detection of All Bacteria and Fungi in Real Time Jeanine P. Wiener-Kronish, MD
1:00 - 1:30 PM	Biomedical Informatics for Critical Care Geoffrey T. Manley, MD, PhD
1:30 - 2:00 PM	Machine Learning: An Adjunct to Defining Phenotypes for Predictive Medicine Michael D. Caldwell, MD, PhD
2:00 - 2:15 PM	Panel Discussion
2:15 - 2:30 PM	Break

**Computational Tool Kits**
Leader: Peter Munson, PhD
2:30 - 3:00 PM	Taxonomizing Diseases: Exploring Genomic Nosologies Using Translational Bioinformatics Atul J. Butte, MD, PhD
3:00 - 3:30 PM	Critical Review of Published Microarray Studies for Cancer Outcome Do’s and Don’ts in Design, Analysis and Reporting Richard M. Simon DSc
3:30 - 4:00 PM	Statistical Methods in Physiomics - Clinical Tools and Research Tools Michael Imhoff, MD, PhD
4:00 - 4:15 PM	Panel Discussion

**Conclusions**
4:15 - 4:35 PM	J. Perren Cobb, MD Symposium Concludes Second Annual Meeting NIH Critical Illness and Injury Scientific Interest Group (CII-SIG) Meeting Time and Place November 15, 2007 4:40 pm, or just after the close of the Symposium Natcher Conference Center Balcony Room A Steering Committee Scott D. Somers, PhD National Institute of General Medical Sciences, NIH, DHHS Anthony F. Suffredini, MD Critical Care Medicine Department, Clinical Center, NIH, DHHS