Derek C. Angus, MD, MPH, FRCP, FCCM, FCCP
CRISMA Laboratory
University of Pittsburgh School of Medicine
Pittsburgh, Pennsylvania

Presentation Title
A Translational Research Paradigm for Critical Care

Dr. Angus is a Professor in the Departments of Critical Care Medicine, Medicine and Health Policy Management, Vice Chair of Research in the Department of Critical Care Medicine, and Director of the CRISMA (Clinical Research, Investigation, and Systems Modeling of Acute Illness) Laboratory at the University of Pittsburgh in Pittsburgh, Pennsylvania.  He acquired training at both the University of Glasgow and University of Pittsburgh, including spending a year in Hong Kong with Medicins Sans Frontieres.

Dr. Angus’ main research interests have focused on clinical, epidemiologic, and translational issues relating to sepsis, pneumonia, acute lung injury and multisystem organ failure and on health services deliver issues relating to critical care. From July 1 through December 31, 2006, Dr. Angus was on sabbatical at the Cochin Hospital / University of Paris V in the Department of Critical Care Medicine, headed by Jean-Francois Dhainaut, who is also President of the University. He was working with Jean-Daniel Chiche and Jean-Paul Mira to conduct translational and clinical research related to sepsis and critical care. 

Recently, Dr. Angus received $8.4 M from the National Institute of General Medical Sciences (NIGMS) to fund the ProCESS (Protocolized Care for Early Septic Shock) study focusing on how to best treat sepsis. In addition, he is leading three large NIH multicenter studies in the critically ill - GenIMS (Genetic and Inflammatory Markers of Sepsis), EA-PAC (Economic Analysis of the Pulmonary Artery Catheter), and PrONOx (Prolonged Outcomes after Nitric Oxide for Premature Ventilated Babies). 

Beginning December 1, 2006, Dr. Angus began his appointment as Contract Editor for JAMA with focus on pulmonary and critical care medicine.