SPEAKERS
- Luis A. Nunes Amaral, PhD
- Keith Baggerly, PhD
- Jeremy M. Berg, PhD
- Andrew Bersten, MD
- Trinad Chakraborty, PhD
- Augustine Choi, MD
- John Cidlowski, PhD
- Bruce Freeman, PhD
- Mark T. Gladwin, MD
- Brahm Goldstein, MD
- David S. Goldstein, MD, PhD
- Ramona Hicks, PhD
- Marti Jett, PhD
- Teri Manolio, MD, PhD
- John Marshall, MD
- Christian Meisel, MD
- Sidney M. Morris, PhD
- Avery Nathens, MD, PhD, MPH
- Carol E. Nicholson, MD
- Frank R Sharp, MD
- Alan R. Shuldiner, MD
- Robert Vandre, COL
- Richard M. Weinshilboum, MD
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John C. Marshall, MD
University of Toronto
Toronto, Ontario
Speaker Topic
Canadian Critical Care Trials Network
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John C. Marshall is a Professor of Surgery in the Department of Surgery and a member of the Interdepartmental Division of Critical Care Medicine at the University of Toronto, and a critical care surgeon at St. Michael’s Hospital. His clinical interests are sepsis, trauma, and critical care. He is a graduate at the University of Toronto and undertook his surgical training at Dalhousie University in Halifax, followed by a research fellowship in surgical immunobiology and critical care at McGill University.
Dr. Marshall’s academic interests are sepsis and the dynamics of host-microbial interactions. His CIHR-funded laboratory studies the mechanisms that regulate neutrophil survival in sepsis and critical illness through modulation of programmed cell death or apoptosis in the neutrophil. Current areas of focus of his graduate students and research associates are a novel inflammatory cytokine – Pre-B cell colony enhancing factor (P-BEF) - and the role of tyrosine phosphorylation in the regulation of apoptotic enzyme activity. He also maintains an interest in clinical trials and is the senior investigator of the AATICC (Appropriate Antimicrobial Therapy in Critical Care) program, whose cornerstone is a multi-center pilot study comparing broad-spectrum antibiotics to placebo in the management of critically ill patients with suspected ICU-acquired infection. He has been actively involved in the design and conduct of clinical trials in sepsis, serving as an advisor to a number of pharmaceutical companies undertaking research in this area, and has a particular interest in outcome measures in clinical trials. He serves as the Chair of the Canadian Critical Care Trials Group and as the Treasurer and Chair-Elect of the International Sepsis Forum. Dr. Marshall has published more than 170 peer reviewed papers and 65 chapters and has edited 2 books. He is on a number of Editorial Boards including Shock, Critical Care, and Current Opinion in Critical Care. |
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