Dr. Goldstein graduated from Yale College and Johns Hopkins School of Medicine (MD PhD in Behavioral Science). He has been tenured at the NIH since 1984 and has directed the Clinical Neurocardiology Section in intramural NINDS since 1999. He has received Yale’s Angier Prize for Research in Psychology, the Laufberger Medal of the Czech Academy of Sciences, the Presidential Executive Director’s Award of the National Dysautonomia Research Foundation, two NIH Merit Awards, and the NIH Distinguished Clinical Teacher Award. He is the author of Stress, Catecholamines, and Cardiovascular Disease (1995), The Autonomic Nervous System in Health and Disease (2001), The NDRF Handbook for Patients with Dysautonomias (2002), and Adrenaline and the Inner World: An Introduction to Scientific Integrative Medicine (2006). His research on stress, catecholamine systems, dysautonomias, and clinical neurocardiologic disorders has been published in more than 440 papers, which have been cited more than 12,000 times. A world authority on clinical catecholamine neurochemistry and autonomic function testing, he developed numerous clinical laboratory methods including liquid chromatography with electrochemical detection for plasma levels of norepinephrine and adrenaline, 6-[18F]fluorodopamine PET scanning, and brainstem imaging using the NIH’s High Resolution Research Tomograph. His main discoveries have been about cardiac noradrenergic denervation in Parkinson disease (PD), orthostatic hypotension from sympathetic denervation and baroreflex failure in PD, differential regulation of the sympathetic noradrenergic and adrenomedullary hormonal systems in stress and distress, sympathoadrenal imbalance attending neurocardiogenic syncope, and autoimmune autonomic failure from a circulating antibody to the neuronal nicotinic cholinergic receptor. He has developed a comprehensive homeostatic theory of stress, distress, allostatic load, and acute and chronic diseases. His main career goal is to introduce scientific integrative medicine into teaching, research, and clinical practice.