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Functional Genomics of Critical Illness and Injury - Surviving Stress - From Organ Systems to Molecules


Mark T. Gladwin, MD
National Heart Lung and Blood Institute, NIH, DHHS
Bethesda, Maryland

Speaker Topic
Nitrite as an Intrinsic Signaling Molecule That Regulates Hypoxic NO Homeostasis and Cytoprotection

 

Mark Gladwin received his Doctor of Medicine from the University of Miami Honors Program in Medical Education in 1991. After completing his internship and chief residency at the Oregon Health Sciences University in Portland, Oregon, Dr. Gladwin joined the National Institutes of Health (NIH) in 1995 as a critical care fellow at the Clinical Center. After a one-year clinical fellowship in pulmonary medicine at the University of Washington in Seattle, he returned to the NIH Clinical Center for a research fellowship in the Critical Care Medicine Department under the mentorship of Drs. James Shelhamer, Frederick Ognibene, Alan Schechter, and Richard Cannon.


In 2005, Dr. Gladwin was appointed Chief of the new Vascular Medicine Branch in the Division of Intramural Research at NIH's National Heart, Lung, and Blood Institute (NHLBI). As branch chief, he oversees a robust portfolio of studies to define the cellular and molecular mechanisms that underlie normal physiological function and disease processes of the lungs and their vasculature and fosters collaborations with researchers in the NIH Critical Care Medicine Department to ensure strong and smooth interactions among laboratory and clinical investigations.

He has been involved in enrolling more than 700 patients in more than a dozen studies at the NIH Clinical Center and has co-authored 82 published peer-reviewed manuscripts addressing biochemical mechanisms involved in blood vessel relaxation and contraction.

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