Lyle L. Moldawer, PhD
Professor of Surgery
Vice Chairman for Research
University of Florida College of Medicine
Gainesville, Florida

Speaker Topic: Inflammation and Host Response

Dr. Moldawer joined the Department of Surgery, University of Florida College of Medicine faculty in September, 1993, after spending seven years on the faculty of Cornell University Medical College, first as an Assistant and then Associate Professor of Surgery, and Associate Professor of Cell Biology and Anatomy. He received his Ph.D. in experimental medicine from the Medical Faculty at the University of Gothenburg, Gothenburg, Sweden, in 1986. His research interests have focused on the pathophysiologic role of cytokines in the host response to acute and chronic inflammation.

Dr. Moldawer currently lists 261 peer-reviewed publications. He has received independent funding from the National Institutes of Health continuously since 1988. During this period, Dr. Moldawer has pursued research into the role that dysregulation between proinflammatory cytokine and cytokine inhibitor production plays in the pathologic host response to acute inflammatory processes, such as sepsis and systemic inflammatory response syndromes, and to chronic inflammatory processes, such as cancer and AIDS-associated cachexia. In 1998 Dr. Moldawer received the Merit Award from the National Institute of General Medical Sciences, extending his current NIH support through the year 2006. Dr. Moldawer is also co-Director of the Protein Analysis and Cell Biology Core, and a member of the Steering Committee, of a National Institute of General Medical Sciences Large Scale Collaborative Research Program (Glue Grant) entitled "Inflammation and the Host Response to Injury," funded through 2006 to introduce functional genomics and high throughput proteomics into trauma and sepsis research.  

In the teaching arena, Dr. Moldawer is the principal investigator on a training grant from NIH to provide surgical residents in training with a two-year research stint in molecular biology and gene therapy. He is one of only a small number of Ph.D.'s in the country who holds the academic rank of Full Professor in a department of surgery. Since 1988, Dr. Moldawer has trained 31 surgical residents in research methodologies (19 at the University of Florida). Sixteen of these surgical residents have continued in academic training programs, and eight are currently on the faculty of colleges of medicine.

Dr. Moldawer has sat on or currently sits on the editorial board of five journals, including: the American Journal of Physiology, Journal of Parenteral and Enteral Nutrition, Surgical Infections,and Shock. He is an Associate Editor of Shock and the American Journal of Physiology, as well as Section Editor of Current Opinion in Clinical Nutrition and Metabolic Care. He is a past member of the Metabolic Pathology Study Section of NIH; a current ad hoc member of the Surgery, Anesthesiology, and Trauma Study Section; and serves in special initial review groups for the National Institute of General Medical Sciences in the fields of graduate medical education and burn and trauma physiology.